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The key point: the best option depends on the reason for low B12 and your clinical context

Consequently, current therapies are reactive rather than preventive, highlighting the critical need for disease-modifying treatments that target underlying pathophysiology

There are practical reasons too: B can be unstable if mixed with certain other vitamins in solution, and dosing schedules for B deficiency (pernicious anemia, for instance) may differ

An analysis of the ELIXA trial data indicated that short-term GLP-1RAs may also have renal protective effects, analogous to long-acting GLP-1RAs [47]

Xiao, Engineered exosomes for targeted co-delivery of MiR-21 inhibitor and chemotherapeutics to reverse drug resistance in colon cancer